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Treatment with steroids for acute psychosis associated with multiple sclerosis
INTRODUCTION. Psychiatric disorders are common in patients suffering from multiple sclerosis (MS). Psychosis is a rare complication in this condition. We present two patients with MS and psychosis. CLINICAL CASES. Case 1. A 45yearold man was admitted to the hospital because an acute psychosis. The diagnosis of clinical definitive MS was made two years before. Cranial magnetic resonance imaging (MRI) and single positron emission computerized tomography (SPECT) showed lesions in the left temporal lobe. He was treated with a 3day course of highdose corticosteroid and neuroleptic. The patient’s status gradually improved within the following weeks. Case 2. A 41yearold man with MS was hospitalized in a Psychiatric Department for acute psychosis. He was treated with highdose of neuroleptic. Thereafter two remissions and relapses of MS have occurred. In 1998, the patient was evaluated in the Service of Psychiatric for new paranoid acute psychosis.