Tabla. Tratamientos inicial y actual de los pacientes (número de casos). |
||
Inicial |
Actual |
|
Metilfenidato de liberación inmediata solo |
8 |
0 |
Metilfenidato de liberación intermedia solo |
6 |
4 |
Metilfenidato de liberación inmediata + intermedia |
4 |
1 |
Metilfenidato de liberación prolongada |
4 |
8 |
Metilfenidato de liberación prolongada + otros |
0 |
0 |
Otras combinaciones |
0 |
0 |
Lisdexanfetamina |
0 |
6 |
Lisdexanfetamina + liberación inmediata |
0 |
0 |
Neurofibromatosis type 1 and attention-deficit disorder. Our current experience Introduction. Patients with neurofibromatosis type 1 (NF1) have a high predisposition to develop attention-deficit disorder. The aim of this study is to determine the prevalence of NF1 patients with attention-deficit/hyperactivity disorder (ADHD) diagnosis attending our Child Neurology Department. We assess patient adherence and medical treatment outcomes. Patients and methods. Identification of patients with NF1 being followed up from December 31 2015 to June 31 2017 with ADHD diagnosis. Clinical and treatment data were collected. Results. 56 patients with NF1 were enrolled in the study with a mean age of 9.83 ± 4.17 years. 23 patients (41%) were diagnosed with ADHD, mean age at ADHD diagnosis of 7.53 ± 2.46 years. School-age children with ADHD represented 48.8% of cases. All but one of the children received treatment, mean duration of treatment was 3.85 ± 3.04 years. 19 out of 22 patients (86%) continue medical treatment. Positive effects were reported by eleven patients with a moderate response in eight patients. Conclusions. Prevalence of ADHD in patients with NF1 is high. Early diagnosis and treatment of ADHD in patients with NF1 is highlighted by this study. Our study reveals good patient adherence and medical treatment outcomes in most patients. Key words. Attention-deficit disorder. Attention-deficit/hyperactivity disorder. Central nervous system stimulants. Lysdexamphetamine. Methylphenidate. Neurofibromatosis type 1. |