Neurologia.com es una comunidad de conocimiento alrededor de la neurología en habla hispana, compuesta por millones de profesionales, desde estudiantes a instituciones médicas o académicas. Esta comunidad se dota de diferentes herramientas de interrelación y difusión del conocimiento en neurociencia
Drug-induced parkinsonism. Clinical aspects compared with parkinson disease
INTRODUCTION. Drug-induced Parkinsonism (DIP) is the second commonest cause of Parkinson syndromes, after Parkinson disease (PD) and represents between 10% and 30% of all patients with Parkinsonism. OBJECTIVES. To study the frequency and drugs responsible for DIP and to compare some of the clinical characteristics of these patients and those with PD.
PATIENTS AND METHODS. A retrospective community based study in Bajo Aragon district to determine the frequency of PD and other Parkinsonism, including DIP. PD was diagnosed on the criteria proposed by the United Kingdom Parkinson’s Disease Society Brain Bank and DIP on the criteria of Jiménez et al.
RESULTS. Calcium antagonists were the cause of 73% of the DIP, followed by neuroleptic drugs (11.5%). There were 73% women (19/26). The patients with DIP were older than those with PD when their symptoms started (p= 0.02). In patients with DIP, 48% presented with bilateral symptoms as compared with 7% in PD (p< 0.0001).